Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.69 |
| ▸ | KDM5A | P29375 | 5/20 | 0.69 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.69 |
| ▸ | PHF8 | Q9UPP1 | 10/20 | 0.57 |
| ▸ | KDM4A | O75164 | 3/20 | 0.51 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244234 | 0.86 | KDM4C (0.54) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL18579672 | 0.82 | KDM4C (0.67) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL16032985 | 0.81 | KDM4C (1.00) | KDM4CKDM5AKDM5BKDM4AKDM2B | |
| SCHEMBL16033169 | 0.81 | KDM4C (0.82) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL16035092 | 0.80 | PHF8 (0.67) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL20106599 | 0.77 | KDM4C (0.60) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL17604513 | 0.77 | KDM4C (0.70) | KDM4CKDM5AKDM5BPHF8KDM2B | |
| SCHEMBL20978856 | 0.76 | KDM4C (0.68) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL16033706 | 0.76 | KDM4C (1.00) | KDM4CKDM5AKDM5BPHF8KDM4A | |
| SCHEMBL17898916 | 0.75 | KDM4C (0.67) | KDM4CKDM5AKDM5BPHF8KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |