Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 8/20 | 0.60 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.56 |
| ▸ | KDM5A | P29375 | 5/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 5/20 | 0.56 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19383187 | 0.82 | PHF8 (0.56) | PHF8KDM4CKDM5AKDM5BKDM2B | |
| SCHEMBL19383296 | 0.77 | PHF8 (0.61) | PHF8KDM4CKDM5AKDM5BKDM2B | |
| SCHEMBL19383508 | 0.75 | KDM4C (0.54) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL17604646 | 0.75 | PHF8 (0.70) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19383314 | 0.74 | KDM2B (0.47) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL20978854 | 0.74 | KDM4C (0.70) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL19383189 | 0.72 | PHF8 (0.55) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL16034026 | 0.72 | KDM4C (1.00) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL24244153 | 0.72 | PHF8 (0.45) | PHF8KDM4CKDM5AKDM5BKDM4A | |
| SCHEMBL24244251 | 0.72 | PHF8 (0.59) | PHF8KDM4CKDM5AKDM5BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3436445-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2023-09-06 | — | — | EP | disclosed |
| EP-3193881-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2022-02-09 | — | — | EP | disclosed |