Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22735934 | 0.69 | BRD4 (1.00) | BRD4 | |
| SCHEMBL22735880 | 0.68 | BRD4 (0.59) | BRD4SMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL25547142 | 0.66 | CA12 (0.83) | CNR2SMN1; SMN2LMNAHTTCA12 | |
| SCHEMBL22735689 | 0.65 | TP53 (0.51) | BRD4LMNAPOLB | |
| SCHEMBL17827613 | 0.63 | CA12 (0.73) | CNR2SMN1; SMN2LMNAHTTCA12 | |
| SCHEMBL3567852 | 0.63 | CA12 (0.67) | CNR2SMN1; SMN2LMNAHTTCA12 | |
| SCHEMBL5960116 | 0.62 | MEN1 (0.73) | CNR2SMN1; SMN2LMNAHTTCA12 | |
| SCHEMBL13972835 | 0.61 | CA12 (0.69) | CNR2SMN1; SMN2LMNAHTTCA12 | |
| SCHEMBL22735932 | 0.61 | BRD4 (0.84) | BRD4 | |
| SCHEMBL13959239 | 0.60 | CA12 (0.67) | CNR2SMN1; SMN2LMNAHTTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707139-B1 | XANTHINE DERIVATIVES AND USES THEREOF AS INHIBITORS OF BROMODOMAINS OF BET PROTEINS | CENTRE NAT RECH SCIENT (FR) | 2022-02-16 | — | — | EP | disclosed |