Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.59 |
| ▸ | BRD2 | P25440 | 1/20 | 0.57 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.57 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22734757 | 0.84 | BRD4 (0.52) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22734479 | 0.83 | BRD4 (0.60) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22735699 | 0.83 | BRD4 (0.59) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22400721 | 0.82 | BRD4 (0.73) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22735701 | 0.80 | BRD4 (0.59) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22735695 | 0.79 | BRD4 (0.64) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22734660 | 0.79 | BRD4 (0.64) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22735940 | 0.79 | BRD4 (0.67) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22735675 | 0.78 | BRD4 (0.62) | BRD4BRD2BRD3BRDT | |
| SCHEMBL22735797 | 0.78 | BRD4 (0.75) | BRD4BRD2BRD3BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707139-B1 | XANTHINE DERIVATIVES AND USES THEREOF AS INHIBITORS OF BROMODOMAINS OF BET PROTEINS | CENTRE NAT RECH SCIENT (FR) | 2022-02-16 | — | — | EP | disclosed |