SCHEMBL2425

SCHEMBL2425

BrC1(Br)COCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11382309 0.75
SCHEMBL8145941 0.67
SCHEMBL2032718 0.67 TTR (0.33)
SCHEMBL28653172 0.65
SCHEMBL793259 0.62
SCHEMBL4617263 0.62
SCHEMBL9681485 0.62
SCHEMBL21841415 0.62
SCHEMBL15052687 0.62
SCHEMBL8151951 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011141933-A2 PROCESS FOR PREPARATION OF 2-[3-CYANO-4-(2-METHYLPROPOXY)PHENYL]-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS MSN LABORATORIES LIMITED (IN) 2011-11-17 WO claimed
JP-4711950-B2 2011-06-29 JP claimed
EP-1633750-B1 SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES EISAI R&D MAN CO LTD (JP) 2010-12-01 EP claimed
US-7652137-B2 Substitued azaindoline intermediate for use in the manufacture of 5-substituted 7-azaindolines and 5-substituted 7-azaindoles; pharmaceutical intermediates EISAI R & D MANAGEMENT CO., LTD. (JP) 2010-01-26 US claimed
US-7271302-B1 Method for brominating organic compounds MERCK PATENT GESELLSCHAFT (DE) 2007-09-18 US claimed
US-20060235042-A1 Synthesis EISAI CO., LTD. (JP) 2006-10-19 US claimed
JP-2006520771-A 2006-09-14 JP claimed
EP-1633750-A2 SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAINDOLINES Eisai Co., Ltd. (JP) 2006-03-15 EP claimed
WO-2004078757-A2 SYNTHESIS OF 5-SUBSTITUTED 7-AZAINDOLES AND 7-AZAIDONINES EISAI CO., LTD. (JP) 2004-09-16 WO claimed
EP-0628032-B1 QUINAZOLINONE ANTIANGINAL AGENTS PFIZER LTD (GB) 1998-05-13 EP claimed
JP-2525126-B2 PFIZER 1996-08-14 JP claimed
EP-0628032-A1 QUINAZOLINONE ANTIANGINAL AGENTS Pfizer Limited (GB) 1994-12-14 EP claimed
WO-1993012095-A1 QUINAZOLINONE ANTIANGINAL AGENTS PFIZER LIMITED (GB) 1993-06-24 WO claimed
EP-0168852-B1 AZETIDINE DERIVATIVES AND THEIR PREPARATION SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-07-26 EP claimed
EP-0054795-B1 NOVEL HALOGENATED PROSTACYCLINS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF TEIJIN LIMITED (JP) 1987-07-15 EP claimed
EP-0054795-A2 Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof TEIJIN LIMITED (JP) 1982-06-30 EP claimed
JP-55079336-A None JP disclosed
EP-3778667-B1 4-METHYL-1-PENTENE POLYMER PARTICLES AND METHOD OF PRODUCING 4-METHYL-1-PENTENE RESIN MITSUI CHEMICALS INC (JP) 2025-09-03 EP disclosed
US-4035415-A GASTROINTESTINAL DISORDERS CARLO ERBA, S.P.A. (IT) 1977-07-12 US disclosed
US-3935009-A FLUOREN-9-YLIDENE OCE-VAN DER GRINTEN N.V. (NL) 1976-01-27 US disclosed