Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17137442 | 1.00 | IRAK4 (0.38) | IRAK4FUCA1 | |
| SCHEMBL21338617 | 1.00 | IRAK4 (0.38) | IRAK4FUCA1 | |
| SCHEMBL17137459 | 0.81 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL21338625 | 0.81 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL24249977 | 0.81 | IRAK4 (0.43) | IRAK4 | |
| SCHEMBL21338555 | 0.77 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL24250241 | 0.77 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL17137393 | 0.77 | IRAK4 (0.35) | IRAK4 | |
| SCHEMBL1644475 | 0.75 | MGAM (0.33) | IRAK4 | |
| SCHEMBL23706795 | 0.74 | IRAK4 (0.39) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536685-B1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS AND THEIR USE AS IRAK4 INHIBITORS | PFIZER (US) | 2022-02-16 | — | — | EP | disclosed |