Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20130905 | 0.82 | IRAK4 (0.65) | IRAK4 | |
| SCHEMBL20130876 | 0.82 | IRAK4 (0.73) | IRAK4 | |
| SCHEMBL21325853 | 0.81 | IRAK4 (0.63) | IRAK4 | |
| SCHEMBL17148584 | 0.80 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL18271551 | 0.77 | IRAK4 (0.66) | IRAK4 | |
| SCHEMBL17148583 | 0.77 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17148581 | 0.77 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL21772248 | 0.77 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17137518 | 0.77 | IRAK4 (1.00) | IRAK4 | |
| SCHEMBL17137517 | 0.77 | IRAK4 (1.00) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536685-B1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS AND THEIR USE AS IRAK4 INHIBITORS | PFIZER (US) | 2022-02-16 | — | — | EP | disclosed |