Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24250232 | 0.92 | IRAK4 (0.75) | IRAK4KCNH2 | |
| SCHEMBL30196522 | 0.85 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL17136940 | 0.85 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL20130928 | 0.85 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL17137603 | 0.80 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL21327707 | 0.80 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL30196813 | 0.80 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL24250059 | 0.80 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL17137129 | 0.80 | IRAK4 (1.00) | IRAK4KCNH2 | |
| SCHEMBL30196640 | 0.80 | IRAK4 (1.00) | IRAK4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536685-B1 | BICYCLIC-FUSED HETEROARYL OR ARYL COMPOUNDS AND THEIR USE AS IRAK4 INHIBITORS | PFIZER (US) | 2022-02-16 | — | — | EP | disclosed |