Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.66 |
| ▸ | KIT | P10721 | 7/20 | 0.66 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.62 |
| ▸ | BCR | P11274 | 15/20 | 0.62 |
| ▸ | LYN | P07948 | 3/20 | 0.62 |
| ▸ | EGFR | P00533 | 2/20 | 0.62 |
| ▸ | PLK4 | O00444 | 1/20 | 0.62 |
| ▸ | DDX3X | O00571 | 1/20 | 0.62 |
| ▸ | GAK | O14976 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.62 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | RAF1 | P04049 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29552078 | 1.00 | ABL1 (0.66) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL24251031 | 1.00 | ABL1 (0.66) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL29551790 | 0.96 | ABL1 (0.69) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL24251138 | 0.96 | ABL1 (0.69) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL29551810 | 0.96 | ABL1 (0.65) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL24250963 | 0.96 | ABL1 (0.65) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL29551270 | 0.96 | ABL1 (0.69) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL24250904 | 0.96 | ABL1 (0.69) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL24251052 | 0.95 | ABL1 (0.64) | ABL1KITPDGFRBPDGFRABCR | |
| SCHEMBL29551562 | 0.95 | ABL1 (0.64) | ABL1KITPDGFRBPDGFRABCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |