Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 15/20 | 0.69 |
| ▸ | ABL1 | P00519 | 10/20 | 0.69 |
| ▸ | KIT | P10721 | 7/20 | 0.69 |
| ▸ | BCR | P11274 | 7/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | PRKCA | P17252 | 1/20 | 0.65 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29551247 | 1.00 | PDGFRA (0.69) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL24251132 | 1.00 | PDGFRA (0.69) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL29552044 | 0.95 | PDGFRA (0.77) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL24251012 | 0.95 | PDGFRA (0.77) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL24251133 | 0.94 | PDGFRA (0.68) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL29551537 | 0.92 | PDGFRA (0.71) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL24251016 | 0.92 | PDGFRA (0.71) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL29551241 | 0.91 | ABL1 (0.62) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL24250918 | 0.91 | ABL1 (0.62) | PDGFRAABL1KITBCRPDGFRB | |
| SCHEMBL24251051 | 0.90 | PDGFRA (0.75) | PDGFRAABL1KITBCRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |