Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.53 |
| ▸ | BCR | P11274 | 16/20 | 0.53 |
| ▸ | KIT | P10721 | 8/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | PLK4 | O00444 | 1/20 | 0.51 |
| ▸ | DDX3X | O00571 | 1/20 | 0.51 |
| ▸ | GAK | O14976 | 1/20 | 0.51 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24251136 | 1.00 | ABL1 (0.53) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24250982 | 0.93 | ABL1 (0.60) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24251101 | 0.92 | ABL1 (0.55) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24251100 | 0.91 | ABL1 (0.54) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24251178 | 0.90 | ABL1 (0.52) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24250921 | 0.90 | ABL1 (0.52) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24250927 | 0.90 | ABL1 (0.58) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL24251091 | 0.89 | ABL1 (0.54) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL28699576 | 0.89 | ABL1 (0.55) | ABL1BCRKITPDGFRBPDGFRA | |
| SCHEMBL29551550 | 0.89 | ABL1 (0.55) | ABL1BCRKITPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127065-A | Compounds for the treatment of neurodegenerative diseases and cancer | 鸿仪有限责任公司 | 2022-03-01 | — | — | CN | claimed |