Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 10/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20036912 | 0.96 | PDK2 (0.38) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL24527187 | 0.96 | PDK2 (0.36) | PDK2HTTNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL20962826 | 0.96 | PDK2 (0.42) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL24646511 | 0.96 | PDK2 (0.39) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL15178611 | 0.96 | PDK2 (0.39) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL24612847 | 0.96 | PDK2 (0.42) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL21446615 | 0.94 | PDK2 (0.36) | PDK2 | |
| SCHEMBL23936083 | 0.94 | PDK2 (0.36) | PDK2 | |
| SCHEMBL19197425 | 0.93 | PDK2 (0.40) | PDK2MLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL23936792 | 0.93 | PDK2 (0.37) | PDK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220052271-A1 | A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2022-02-17 | — | — | US | disclosed |