Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467688 | 1.00 | PRMT5 (0.38) | PRMT5WDR77BCHECNR2CYP1A2 | |
| SCHEMBL25248371 | 0.88 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19ALDH1A1CLK4 | |
| SCHEMBL30467568 | 0.88 | CYP1A2 (0.38) | BCHECNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL24252850 | 0.88 | CYP1A2 (0.38) | BCHECNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL25212977 | 0.86 | CYP1A2 (0.37) | BCHECNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL31753942 | 0.86 | CYP1A2 (0.37) | BCHECNR2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30467817 | 0.86 | PRMT5 (0.37) | PRMT5WDR77BCHECNR2CYP1A2 | |
| SCHEMBL30467599 | 0.86 | PRMT5 (0.37) | PRMT5WDR77BCHECNR2CYP1A2 | |
| SCHEMBL26781139 | 0.86 | PRMT5 (0.37) | PRMT5WDR77BCHECNR2CYP1A2 | |
| SCHEMBL24252325 | 0.86 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19ALDH1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | PRMT5 2513/4885WDR77 2935/4885BCHE 101/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | PRMT5 2513/4885WDR77 2935/4885BCHE 101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.