Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 18/20 | 1.00 |
| ▸ | CD274 | Q9NZQ7 | 18/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390666 | 1.00 | PDCD1 (1.00) | PDCD1CD274HDAC6HDAC1 | |
| SCHEMBL26075235 | 0.93 | PDCD1 (0.88) | PDCD1CD274HDAC6HDAC1 | |
| SCHEMBL29390063 | 0.91 | PDCD1 (1.00) | PDCD1CD274HDAC6 | |
| SCHEMBL24253012 | 0.91 | PDCD1 (1.00) | PDCD1CD274HDAC6 | |
| SCHEMBL32689504 | 0.88 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL24252532 | 0.88 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL26075238 | 0.87 | PDCD1 (0.86) | PDCD1CD274 | |
| SCHEMBL25245920 | 0.86 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL30591211 | 0.86 | PDCD1 (1.00) | PDCD1CD274 | |
| SCHEMBL24253014 | 0.86 | PDCD1 (1.00) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583822-B2 | Benzylamine derivative, preparation method therefor and use thereof | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2026-03-24 | — | — | US | claimed |
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | claimed |
| CN-114075123-A | Benzylamine derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-02-22 | — | — | CN | claimed |
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022033303-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CD274, PDCD1, PDCD1LG2 | PDCD1 2/4885CD274 1/4885HDAC6 1976/4885 |
| US-12583822-B2 | Benzylamine derivative, preparation method therefor and use thereof | CD274, PDCD1, PDCD1LG2 | PDCD1 2/4885CD274 1/4885HDAC6 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.