SCHEMBL24252545

SCHEMBL24252545

COc1cc(NCc2cccc(-c3ccccc3)c2C)c(C)cc1C=O

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 19/20 0.63
PDCD1 Q15116 11/20 0.63
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24253034 0.89 CD274 (0.65) CD274PDCD1
SCHEMBL24253097 0.89 CD274 (0.65) CD274PDCD1
SCHEMBL24253095 0.88 CD274 (0.67) CD274PDCD1
SCHEMBL24253046 0.82 CD274 (0.66) CD274PDCD1
SCHEMBL24252957 0.81 PDCD1 (0.70) CD274PDCD1
SCHEMBL24252548 0.81 PDCD1 (0.71) CD274PDCD1
SCHEMBL25289256 0.78 PDCD1 (1.00) CD274PDCD1
SCHEMBL29392588 0.78 PDCD1 (1.00) CD274PDCD1
SCHEMBL24253007 0.78 PDCD1 (1.00) CD274PDCD1
SCHEMBL26075250 0.77 CD274 (0.79) CD274PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4198017-A1 BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF Academy of Military Medical Sciences (CN) 2023-06-21 EP disclosed
WO-2022033303-A1 BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF 中国人民解放军军事科学院军事医学研究院 2022-02-17 WO disclosed