⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253414 | 0.76 | CCR6 (0.31) | — | |
| SCHEMBL22993424 | 0.64 | PDK2 (0.33) | — | |
| SCHEMBL20891233 | 0.63 | HPGD (0.38) | — | |
| SCHEMBL22993266 | 0.61 | ABL1 (0.30) | — | |
| SCHEMBL24253334 | 0.60 | KDM4E (0.34) | — | |
| SCHEMBL24253344 | 0.60 | KDM4E (0.44) | — | |
| SCHEMBL24253321 | 0.60 | NPSR1 (0.36) | — | |
| SCHEMBL15705289 | 0.57 | NPSR1 (0.42) | — | |
| SCHEMBL26141015 | 0.55 | PDK2 (0.40) | — | |
| SCHEMBL25496610 | 0.55 | HPGD (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250080-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LTD (GB) | 2023-08-10 | — | — | US | disclosed |
| US-11613527-B2 | Enzyme inhibitors | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2023-03-28 | — | — | US | disclosed |
| US-20220048894-A1 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-02-17 | — | — | US | disclosed |