Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845421 | 0.90 | CACNA1B (0.65) | CACNA1B | |
| SCHEMBL3247843 | 0.87 | CACNA1B (0.55) | CACNA1B | |
| SCHEMBL66508 | 0.86 | CACNA1B (0.56) | CACNA1BRORC | |
| SCHEMBL66507 | 0.86 | CACNA1B (0.56) | CACNA1BRORC | |
| SCHEMBL65749 | 0.83 | CACNA1B (0.77) | CACNA1B | |
| SCHEMBL66506 | 0.82 | CACNA1B (0.61) | CACNA1BRORC | |
| SCHEMBL66834 | 0.80 | CACNA1B (0.62) | CACNA1B | |
| SCHEMBL66835 | 0.80 | CACNA1B (0.62) | CACNA1B | |
| SCHEMBL16497997 | 0.80 | CACNA1B (0.48) | CACNA1BRORC | |
| SCHEMBL2418250 | 0.79 | CACNA1B (0.51) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367790-A2 | SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | Abbott Laboratories (US) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010062927-A2 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA(C)PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2010-06-03 | — | — | WO | disclosed |