⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106999 | 0.80 | — | — | |
| SCHEMBL4824022 | 0.80 | — | — | |
| SCHEMBL7812097 | 0.76 | — | — | |
| SCHEMBL7981813 | 0.76 | — | — | |
| SCHEMBL23490979 | 0.76 | — | — | |
| SCHEMBL23337415 | 0.67 | — | — | |
| SCHEMBL18921890 | 0.62 | — | — | |
| SCHEMBL14220775 | 0.60 | — | — | |
| SCHEMBL18995257 | 0.60 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL24602914 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230009712-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-12 | — | — | US | disclosed |
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |