Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 1/20 | 0.43 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | SCN11A | Q9UI33 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24008483 | 0.84 | GBA1 (0.70) | GBA1CHRM5ADRA2CSCN1ASCN4A | |
| SCHEMBL2716774 | 0.76 | GBA1 (1.00) | GBA1 | |
| SCHEMBL21003358 | 0.75 | CHRM5 (0.46) | GBA1CHRM5ADRA2CSCN1ASCN4A | |
| SCHEMBL20757014 | 0.75 | CHRM5 (0.46) | GBA1CHRM5ADRA2CSCN1ASCN4A | |
| SCHEMBL2717184 | 0.75 | GBA1 (0.97) | GBA1CHRM5ADRA2C | |
| SCHEMBL26633180 | 0.75 | GBA1 (0.55) | GBA1CHRM5ADRA2CSCN1ASCN4A | |
| SCHEMBL26633178 | 0.75 | GBA1 (0.55) | GBA1CHRM5ADRA2CSCN1ASCN4A | |
| SCHEMBL26633151 | 0.75 | GBA1 (0.55) | GBA1CHRM5ADRA2CSCN1ASCN4A | |
| SCHEMBL14968294 | 0.74 | — | — | |
| SCHEMBL20936956 | 0.73 | CHRM5 (0.56) | GBA1CHRM5ADRA2CSCN1ASCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |