Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20696926 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL12384256 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL14588833 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL24126295 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL12384531 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL23265522 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL255297 | 0.90 | DPP4 (0.43) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL4845915 | 0.90 | TSHR (0.47) | DPP4DPP7TSHRTRPA1TRPM8 | |
| SCHEMBL10409614 | 0.87 | DPP4 (0.40) | DPP4DPP7LMNACYP2C9TSHR | |
| SCHEMBL4840491 | 0.85 | TSHR (0.43) | DPP4DPP7LMNACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |