Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | GJB2 | P29033 | 2/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22640958 | 1.00 | BCHE (0.52) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL22640962 | 1.00 | BCHE (0.52) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL18857344 | 1.00 | BCHE (0.52) | BCHEACHEPDE4DHTR1ASSTR1 | |
| Ammonia Solution, Strong SCHEMBL23705109 | 0.99 | BCHE (0.51) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL18666873 | 0.90 | BCHE (0.49) | BCHEACHEPDE4DHTR1ASLC6A2 | |
| SCHEMBL18896702 | 0.86 | BCHE (0.55) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL18640660 | 0.86 | BCHE (0.55) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL29937530 | 0.86 | BCHE (0.55) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL22316285 | 0.86 | BCHE (0.55) | BCHEACHEPDE4DHTR1ASSTR1 | |
| SCHEMBL19380966 | 0.86 | BCHE (0.55) | BCHEACHEPDE4DHTR1ASSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050020-A1 | INVARIANT NATURAL KILLER T-CELL ACTIVATORS | DECIDUOUS THERAPEUTICS, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| EP-4097138-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | Avila Therapeutics, Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-115066438-A | ASGPR binding compounds for degrading extracellular proteins | 阿维拉治疗公司 | 2022-09-16 | — | — | CN | disclosed |
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |