Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657623 | 0.79 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657723 | 0.77 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657954 | 0.77 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657631 | 0.71 | CREBBP (0.63) | CREBBP | |
| SCHEMBL19657427 | 0.70 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19643782 | 0.70 | CREBBP (1.00) | CREBBP | |
| SCHEMBL30117226 | 0.70 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657514 | 0.70 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657518 | 0.70 | CREBBP (1.00) | CREBBP | |
| SCHEMBL19657520 | 0.70 | CREBBP (1.00) | CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464270-B1 | HETEROCYCLIC INHIBITORS OF CBP/EP300 AND THEIR USE IN THE TREATMENT OF CANCER | GENENTECH INC (US) | 2022-02-23 | — | — | EP | disclosed |