SCHEMBL24258610

SCHEMBL24258610

C[P@]1(=O)OC[C@H]2C[C@@H](n3cnc4c(N)ncnc43)[C@@H]2CO[P@](=O)(S)OC[C@@H]2C[C@@H](O1)[C@H](n1cnc3c(=O)n4ccnc4[nH]c31)O2

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24258599 1.00 STING1 (0.46) STING1
SCHEMBL24258577 1.00 STING1 (0.46) STING1
SCHEMBL21263968 0.95 STING1 (0.48) STING1
SCHEMBL21263870 0.95 STING1 (0.48) STING1
SCHEMBL21263928 0.95 STING1 (0.48) STING1
SCHEMBL21263925 0.95 STING1 (0.48) STING1
SCHEMBL21263969 0.95 STING1 (0.48) STING1
SCHEMBL24258585 0.93 STING1 (0.56) STING1
SCHEMBL24258621 0.91 STING1 (0.44) STING1
SCHEMBL24258566 0.90 STING1 (0.45) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752516-B1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL MYERS SQUIBB CO (US) 2022-02-23 — — EP disclosed
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