SCHEMBL24258657

SCHEMBL24258657

Nc1ncnc2c1ncn2C1C[C@@H]2COP(=O)(S)O[C@H]3CC(n4cnc5c4ncn4ccnc54)O[C@@H]3COP(=O)(S)OC[C@@H]12

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24258643 1.00 STING1 (0.55) STING1
SCHEMBL24258637 1.00 STING1 (0.55) STING1
SCHEMBL20908472 0.92 STING1 (0.64) STING1
SCHEMBL20691397 0.91 STING1 (0.65) STING1
SCHEMBL20692277 0.91 STING1 (0.65) STING1
SCHEMBL24258674 0.91 STING1 (0.43) STING1
SCHEMBL24258559 0.91 STING1 (0.43) STING1
SCHEMBL24258536 0.90 STING1 (0.69) STING1
SCHEMBL24258680 0.90 STING1 (0.69) STING1
SCHEMBL21263824 0.88 STING1 (0.53) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752516-B1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL MYERS SQUIBB CO (US) 2022-02-23 — — EP disclosed
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