Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263397 | 0.92 | TYK2 (0.46) | TYK2ALDH1A1PTK2POLBGAA | |
| SCHEMBL31245741 | 0.92 | TYK2 (0.52) | TYK2 | |
| SCHEMBL24263282 | 0.92 | TYK2 (0.52) | TYK2 | |
| SCHEMBL31245715 | 0.87 | TYK2 (0.51) | TYK2 | |
| SCHEMBL22272872 | 0.85 | TYK2 (0.56) | TYK2ALDH1A1 | |
| SCHEMBL31245700 | 0.85 | TYK2 (0.51) | TYK2 | |
| SCHEMBL20557221 | 0.84 | MAPT (0.39) | ALDH1A1POLBGAAMAPT | |
| SCHEMBL24263286 | 0.83 | TYK2 (0.55) | TYK2 | |
| SCHEMBL24263518 | 0.83 | TYK2 (0.55) | TYK2 | |
| SCHEMBL31245725 | 0.83 | TYK2 (0.55) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |