Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22229005 | 0.91 | TYK2 (1.00) | TYK2 | |
| SCHEMBL24263416 | 0.86 | TYK2 (0.84) | TYK2 | |
| SCHEMBL16812376 | 0.85 | TYK2 (1.00) | TYK2 | |
| SCHEMBL18143581 | 0.85 | TYK2 (1.00) | TYK2 | |
| SCHEMBL24263512 | 0.85 | TYK2 (0.81) | TYK2 | |
| SCHEMBL24263440 | 0.85 | TYK2 (0.80) | TYK2 | |
| SCHEMBL24263441 | 0.85 | TYK2 (0.80) | TYK2 | |
| SCHEMBL24263281 | 0.85 | TYK2 (0.82) | TYK2 | |
| SCHEMBL24263414 | 0.84 | TYK2 (0.77) | TYK2 | |
| SCHEMBL24263483 | 0.84 | TYK2 (0.79) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |