Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754423 | 0.82 | TYK2 (0.59) | TYK2PDE4DSTAT3 | |
| SCHEMBL24263553 | 0.79 | TYK2 (0.51) | TYK2PDE4DSTAT3 | |
| SCHEMBL24263488 | 0.76 | TYK2 (0.50) | TYK2PDE4DSTAT3 | |
| SCHEMBL24263487 | 0.75 | TYK2 (0.66) | TYK2PDE4DSTAT3 | |
| SCHEMBL30452323 | 0.75 | TYK2 (0.61) | TYK2PDE4DSTAT3 | |
| SCHEMBL29754341 | 0.74 | TYK2 (0.60) | TYK2PDE4DSTAT3 | |
| SCHEMBL24263467 | 0.70 | TYK2 (0.65) | TYK2PDE4DSTAT3 | |
| SCHEMBL31245693 | 0.64 | TYK2 (0.39) | TYK2PDE4DSTAT3 | |
| SCHEMBL24263480 | 0.64 | TYK2 (0.78) | TYK2PDE4DSTAT3 | |
| SCHEMBL24263458 | 0.64 | TYK2 (0.63) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |