Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14665281 | 0.83 | HTT (0.42) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL26237869 | 0.81 | UTS2R (0.50) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL20096984 | 0.80 | UTS2R (0.46) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29780042 | 0.78 | BCHE (0.59) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL150044 | 0.78 | BCHE (0.59) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13011424 | 0.78 | SLC22A12 (0.44) | POLBMAPTHPGDCA12CA1 | |
| SCHEMBL28845794 | 0.77 | MAPT (0.47) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL29315992 | 0.76 | BCHE (0.48) | POLBMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL20097038 | 0.76 | UTS2R (0.43) | POLBMEN1KMT2AMAPTHTT | |
| SCHEMBL2098721 | 0.76 | MAPT (0.74) | POLBMEN1KMT2ACYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114733-A1 | KRAS MODULATORS AND USES THEREOF | QUANTA THERAPEUTICS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| US-20220059775-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS USING THE SAME | IDEMITSU KOSAN CO.,LTD. (JP) | 2022-02-24 | — | — | US | disclosed |
| CN-104231023-B | Tricyclic fused heterocycle nucleoside phosphoramidate compound, preparation method and application | 南京汇诚制药有限公司 | 2019-02-05 | — | — | CN | disclosed |
| CN-104231023-A | Tricyclic fused-heterocyclic nucleoside phosphoramidate compound and preparation method and applications of tricyclic fused-heterocyclic nucleoside phosphoramidate compound | NANJING SANHOME PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | disclosed |