Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24264730 | 0.87 | TAAR1 (0.50) | TAAR1SLC18A2SIGMAR1CTSSCTSK | |
| SCHEMBL2628426 | 0.85 | TAAR1 (0.52) | TAAR1SLC18A2SIGMAR1CTSSCTSK | |
| SCHEMBL8318346 | 0.85 | TAAR1 (0.52) | TAAR1SLC18A2SIGMAR1CTSSCTSK | |
| SCHEMBL8175870 | 0.85 | TAAR1 (0.52) | TAAR1SLC18A2SIGMAR1CTSSCTSK | |
| SCHEMBL38479 | 0.83 | MME (0.57) | TAAR1SLC18A2SIGMAR1CYP1A2L3MBTL1 | |
| SCHEMBL38480 | 0.83 | MME (0.57) | TAAR1SLC18A2SIGMAR1CYP1A2L3MBTL1 | |
| SCHEMBL161255 | 0.83 | MME (0.57) | TAAR1SLC18A2SIGMAR1CYP1A2L3MBTL1 | |
| SCHEMBL7937827 | 0.83 | MME (0.57) | TAAR1SLC18A2SIGMAR1CYP1A2L3MBTL1 | |
| SCHEMBL27540746 | 0.82 | NPSR1 (0.52) | CTSSCTSKPAMNPC1RAB9A | |
| SCHEMBL1324550 | 0.81 | MME (0.56) | TAAR1SLC18A2SIGMAR1CYP1A2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022038417-A2 | MODIFIED IL-18 POLYPEPTIDES AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2022-02-24 | — | — | WO | disclosed |