Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | IL1B | P01584 | 2/20 | 0.42 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19619253 | 0.95 | CRBN (0.51) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL20153862 | 0.90 | CRBN (0.61) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL20153897 | 0.86 | CRBN (0.47) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL19629754 | 0.81 | TSHR (0.43) | TSHRALDH1A1CYP1A2 | |
| SCHEMBL22873320 | 0.80 | CRBN (0.45) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL22006041 | 0.80 | TSHR (0.41) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL19629704 | 0.79 | CRBN (0.52) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL21214939 | 0.77 | CRBN (0.51) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL25124019 | 0.76 | CRBN (0.53) | CRBNDDB1IKZF3TSHRALDH1A1 | |
| SCHEMBL22873882 | 0.76 | CRBN (0.51) | CRBNDDB1IKZF3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |