Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.47 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847517 | 0.82 | — | — | |
| SCHEMBL4880783 | 0.80 | EPHX1 (0.50) | EPHX1NAAASMN1; SMN2HTTCYP2C19 | |
| Bicarbonate SCHEMBL9097142 | 0.71 | EPHX1 (0.50) | EPHX1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL331741 | 0.69 | — | — | |
| SCHEMBL168531 | 0.69 | — | — | |
| Acetic Acid SCHEMBL6914578 | 0.69 | EPHX1 (0.48) | EPHX1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL18855728 | 0.68 | EPHX1 (0.92) | EPHX1SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL14984908 | 0.68 | NPY5R (0.38) | EPHX1ALDH1A1EPHX2 | |
| SCHEMBL25766872 | 0.68 | NPY5R (0.38) | EPHX1ALDH1A1EPHX2 | |
| SCHEMBL14421253 | 0.68 | BTK (0.46) | EPHX1SMN1; SMN2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709667-B1 | BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B V (NL) | 2022-04-13 | — | — | EP | disclosed |