⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24269827 | 1.00 | — | — | |
| SCHEMBL24269829 | 1.00 | — | — | |
| SCHEMBL30092463 | 0.75 | — | — | |
| SCHEMBL1723855 | 0.75 | — | — | |
| SCHEMBL19850945 | 0.74 | — | — | |
| SCHEMBL17916098 | 0.73 | — | — | |
| SCHEMBL13210547 | 0.73 | — | — | |
| SCHEMBL13210355 | 0.73 | — | — | |
| SCHEMBL13210365 | 0.73 | — | — | |
| SCHEMBL13210561 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068848-A1 | 3-[(1H-PYRAZOL-4-YL)OXY]PYRAZIN-2-AMINE COMPOUNDS AS HPK1 INHIBITOR AND USE THEREOF | BEIGENE, LTD. (KY) | 2022-04-07 | — | — | WO | disclosed |