Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.63 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 4/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24273500 | 0.91 | PTGER4 (0.68) | PTGER4ABCB1HTTMEN1GAA | |
| SCHEMBL24273062 | 0.88 | PTGER4 (0.61) | PTGER4ABCB1HTTMEN1GAA | |
| SCHEMBL24273429 | 0.87 | PTGER4 (0.66) | PTGER4ABCB1HTTMEN1GAA | |
| SCHEMBL24273524 | 0.87 | PTGER4 (0.60) | PTGER4ABCB1HTTCNR1ALDH1A1 | |
| SCHEMBL24273134 | 0.86 | PTGER4 (0.54) | PTGER4MCL1ABCB1HTTMEN1 | |
| SCHEMBL24273597 | 0.86 | PTGER4 (0.64) | PTGER4ABCB1HTTMEN1GAA | |
| SCHEMBL24273608 | 0.85 | PTGER4 (0.63) | PTGER4ABCB1HTTMEN1GAA | |
| SCHEMBL24273110 | 0.85 | ABCB1 (0.69) | PTGER4ABCB1HTTMEN1GAA | |
| SCHEMBL24273107 | 0.85 | PTGER4 (0.58) | PTGER4ABCB1HTTCNR1CNR2 | |
| SCHEMBL7553691 | 0.83 | PTGER4 (0.69) | PTGER4ABCB1HTTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061008-A2 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |