⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28343056 | 1.00 | — | — | |
| Water SCHEMBL28564295 | 1.00 | — | — | |
| SCHEMBL28556504 | 1.00 | — | — | |
| Cyanate SCHEMBL28268707 | 0.95 | RNPEP (0.34) | — | |
| SCHEMBL28086935 | 0.86 | — | — | |
| SCHEMBL5679030 | 0.76 | — | — | |
| SCHEMBL3687259 | 0.75 | — | — | |
| SCHEMBL11140373 | 0.75 | — | — | |
| SCHEMBL24363633 | 0.73 | — | — | |
| Water SCHEMBL23851225 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116547268-B | Catalytic production of methionine analogues | 安迪苏法国联合股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-115975999-B | Nitrilase and application thereof in synthesis of 2-hydroxy-4-methylthiobutyric acid | 万华化学集团股份有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-119912370-A | Preparation method and reaction device of 2-hydroxy-4-methylthiobutyronitrile | 山东新和成氨基酸有限公司 | 2025-05-02 | — | — | CN | claimed |
| US-12187669-B2 | Method for producing methionine | EVONIK OPERATIONS GMBH (DE) | 2025-01-07 | — | — | US | claimed |
| CN-119219532-A | Preparation method of 2-hydroxy-4-methylthiobutyric acid | 山东新和成氨基酸有限公司 | 2024-12-31 | — | — | CN | claimed |
| US-12172950-B2 | Salt-free production of methionine from methionine nitrile | EVONIK OPERATIONS GMBH (DE) | 2024-12-24 | — | — | US | claimed |
| CN-118759079-A | Method for detecting racemic calcium hydroxymethionine impurity in compound alpha-keto acid tablet | 重庆士立德医药科技有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-115894313-B | Preparation method and production system of 2-hydroxy-4-methylthiobutyrate | 山东新和成氨基酸有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117848995-A | Method for monitoring enzymatic reaction of amide substances, on-line monitoring and automatic control equipment | 北京衍微科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-117825323-A | Modeling method for monitoring content change of each component in amide substance production process | 北京衍微科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| EP-0601195-A1 | PROCESS FOR PRODUCING 2-HYDROXY-4-METHYLTHIOBUTANOIC ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-06-15 | — | — | EP | claimed |
| EP-0330527-B1 | PROCESS FOR THE PREPARATION OF AQUEOUS SOLUTIONS OF 2-HYDROXY-4-METHYLTHIO-BUTYRIC ACID | SOCIEDAD DE DESARROLLO TECNICO INDUSTRIAL (ES) | 1992-09-23 | — | — | EP | claimed |
| US-4912257-A | Process for preparation of aqueous solutions of 2-hydroxy-4-methylthio butyric acid | SOCIEDAD DE DESARROLLO TECNICO INDUSTRIAL (ES) | 1990-03-27 | — | — | US | claimed |
| EP-0142488-B1 | LIQUID 2-HYDROXY-METHYLTHIOBUTYRIC ACID AND PROCESS FOR THE PREPARATION THEREOF | MONSANTO COMPANY (US) | 1987-08-26 | — | — | EP | claimed |
| EP-0143100-B1 | PROCESS FOR THE PREPARATION OF LIQUID 2-HYDROXY-METHYLTHIOBUTYRIC ACID | MONSANTO COMPANY (US) | 1987-08-05 | — | — | EP | claimed |
| US-4524077-A | HYDROLYZING 2-HYDROXY-4-METHYLTHIOBUTYRONITRILE; ANIMAL FEED | MONSANTO COMPANY (US) | 1985-06-18 | — | — | US | claimed |
| EP-0143100-A2 | Process for the preparation of liquid 2-hydroxy-methylthiobutyric acid | MONSANTO COMPANY (US) | 1985-05-29 | — | — | EP | claimed |
| EP-0142488-A2 | Liquid 2-hydroxy-methylthiobutyric acid and process for the preparation thereof | MONSANTO COMPANY (US) | 1985-05-22 | — | — | EP | claimed |
| US-4310690-A | Preparation of the calcium salt of α-hydroxy-gamma-methylmercaptobutyric acid | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-4064159-A | AMMONIATION OF CORRESPONDING ALPHA-HYDROXY DERIVATIVE | PRODUITS CHIMIQUES DU BEARN (FR) | 1977-12-20 | — | — | US | claimed |