Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 15/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 13/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCND3 | P30281 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24277111 | 0.77 | CSNK1E (0.41) | CSNK1ECSNK1DF12 | |
| SCHEMBL24277086 | 0.77 | CSNK1E (0.43) | CSNK1ECSNK1DF12 | |
| SCHEMBL24276951 | 0.77 | CSNK1E (0.36) | CSNK1ECSNK1DF12 | |
| SCHEMBL24276961 | 0.71 | CSNK1E (0.38) | CSNK1ECSNK1DRORC | |
| SCHEMBL24277112 | 0.70 | GRM5 (0.44) | — | |
| SCHEMBL30461913 | 0.69 | CSNK1E (0.38) | CSNK1ECSNK1D | |
| SCHEMBL30461912 | 0.69 | HSP90AA1 (0.34) | CSNK1ECSNK1D | |
| SCHEMBL16728571 | 0.68 | CSNK1E (0.62) | CSNK1ECSNK1D | |
| SCHEMBL24276963 | 0.68 | GLP1R (0.36) | — | |
| SCHEMBL31616861 | 0.68 | GLP1R (0.33) | CSNK1EF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022052958-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-03-17 | — | — | WO | disclosed |