SCHEMBL24277448

SCHEMBL24277448

c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4ccc(-c5cccc6c5Oc5cccc7cccc(c57)O6)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.44
MAPK1 P28482 2/20 0.44
ATM Q13315 2/20 0.44
TYMS P04818 2/20 0.41
PDE6D O43924 1/20 0.33
AHR P35869 1/20 0.32
ALDH1A1 P00352 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
DRD2 P14416 1/20 0.31
HTR7 P34969 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ADRA2A P08913 2/20 0.30
ADRA2B P18089 2/20 0.30
ADRA2C P18825 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24277586 1.00 KDM4E (0.44) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277581 1.00 KDM4E (0.44) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277449 1.00 KDM4E (0.44) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277758 0.99 MAPK1 (0.45) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277759 0.99 MAPK1 (0.45) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277446 0.99 MAPK1 (0.45) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277451 0.99 MAPK1 (0.45) KDM4EMAPK1ATMTYMSPDE6D
SCHEMBL24277753 0.92 KDM4E (0.40) KDM4EMAPK1ATMTYMSALDH1A1
SCHEMBL24277756 0.92 KDM4E (0.40) KDM4EMAPK1ATMTYMSALDH1A1
SCHEMBL24277453 0.91 KDM4E (0.39) KDM4EMAPK1ATMTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022050533-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2022-03-10 WO disclosed