SCHEMBL24277752

SCHEMBL24277752

c1ccc(-c2ccc(N(c3ccc(-c4cccc5ccccc45)cc3)c3ccccc3-c3cccc4c3Oc3cccc5cccc(c35)O4)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
MAPK1 P28482 2/20 0.37
ATM Q13315 2/20 0.37
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
TYMS P04818 1/20 0.34
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24277757 0.99 KDM4E (0.36) KDM4EMAPK1ATMCA12CA1
SCHEMBL24277601 0.97 KDM4E (0.38) KDM4EMAPK1ATMCA12CA1
SCHEMBL24277417 0.93 KDM4E (0.38) KDM4EMAPK1ATMCA12CA1
SCHEMBL24277294 0.93 KDM4E (0.38) KDM4EMAPK1ATMCA12CA1
SCHEMBL24277452 0.93 KDM4E (0.42) KDM4EMAPK1ATMTYMS
SCHEMBL24277754 0.93 KDM4E (0.42) KDM4EMAPK1ATMTYMS
SCHEMBL24277454 0.92 KDM4E (0.41) KDM4EMAPK1ATMTYMS
SCHEMBL24277751 0.92 MAPK1 (0.41) KDM4EMAPK1ATMTYMSALDH1A1
SCHEMBL24277587 0.92 KDM4E (0.41) KDM4EMAPK1ATMTYMS
SCHEMBL24277447 0.92 MAPK1 (0.41) KDM4EMAPK1ATMTYMSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022050533-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2022-03-10 WO disclosed