Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20051708 | 1.00 | HTT (0.40) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL24281758 | 0.97 | HTT (0.40) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL20051709 | 0.97 | HTT (0.40) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL24281721 | 0.94 | KMT2A (0.39) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL20051130 | 0.94 | KMT2A (0.39) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL24281610 | 0.93 | HTT (0.39) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL20051389 | 0.93 | HTT (0.39) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL20051122 | 0.92 | HTT (0.41) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL20050439 | 0.92 | KMT2A (0.39) | HTTLMNAHPGDKMT2AMEN1 | |
| SCHEMBL24281698 | 0.92 | KMT2A (0.39) | HTTLMNAHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971166-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Corteva Agriscience LLC (US) | 2022-03-23 | — | — | EP | disclosed |