Sugi Predict

Sugi Predict / Compounds / SCHEMBL24283269

SCHEMBL24283269

SCHEMBL24283269

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cccc3c2C(=O)N(c2c(-c4ccccc4)cc(-c4ccccc4)cc2-c2ccccc2)C3O)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ATM Q13315 1/20 0.33
▸ LMNA P02545 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ EDNRB P24530 2/20 0.30
▸ EDNRA P25101 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19842367 0.97 MEN1 (0.35) MEN1KMT2AATMLMNANPC1
SCHEMBL19850021 0.92 MEN1 (0.35) MEN1KMT2AATMLMNANPC1
SCHEMBL19842335 0.90 MEN1 (0.37) MEN1KMT2AATMLMNANPC1
SCHEMBL19842859 0.89 MEN1 (0.36) MEN1KMT2AATMLMNANPC1
SCHEMBL19842828 0.85 EDNRB (0.36) MEN1KMT2AATMLMNANPC1
SCHEMBL24282989 0.85 MEN1 (0.43) MEN1KMT2AATMLMNANPC1
SCHEMBL19850152 0.85 MEN1 (0.41) MEN1KMT2AATMLMNANPC1
SCHEMBL19842834 0.84 KMT2A (0.34) MEN1KMT2AATMLMNANPC1
SCHEMBL24282848 0.84 MEN1 (0.40) MEN1KMT2AATMLMNANPC1
SCHEMBL19850149 0.84 MEN1 (0.41) MEN1KMT2AATMLMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3494112-B1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2022-04-20 — — EP disclosed
Send feedback