Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9951247 | 1.00 | MEN1 (0.56) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL14266911 | 1.00 | MEN1 (0.56) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL6888802 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL4167594 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL14280275 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL965611 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL414527 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL16428811 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL9951659 | 0.97 | MEN1 (0.60) | MEN1KMT2ATHRBHTTMAPT | |
| SCHEMBL23045151 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140322785-A1 | Continuous Flow Bioreactor for Magnetically Stabilized Three-Dimensional Tissue Culture | WORCESTER POLYTECHNIC INSTITUTE (US) | 2014-10-30 | — | — | US | disclosed |
| US-20140113835-A1 | CHEMICALLY-DEFINED ARRAYS FOR SCREENING CELL-SUBSTRATE INTERACTIONS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2014-04-24 | — | — | US | disclosed |
| US-8642516-B2 | Chemically-defined arrays for screening cell-substrate interactions | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-02-04 | — | — | US | disclosed |
| US-20130296177-A1 | CHEMICALLY-DEFINED ARRAYS FOR SCREENING CELL-SUBSTRATE INTERACTIONS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-11-07 | — | — | US | disclosed |
| US-20130203145-A1 | Continuous Flow Bioreactor for Magnetically Stabilized Three-Dimensional Tissue Culture | WORCESTER POLYTECHNIC INSTITUTE | 2013-08-08 | — | — | US | disclosed |
| WO-2011112601-A2 | CONTINUOUS FLOW BIOREACTOR FOR MAGNETICALLY STABILIZED THREE-DIMENSIONAL TISSUE CULTURE | WORCESTER POLYTECHNIC INSTITUTE (US) | 2011-09-15 | — | — | WO | disclosed |