SCHEMBL2428386

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2428387	1.00	AHR (0.38)	AHRKMT2AMEN1ACKR3CYP2E1
	SCHEMBL2430784	0.92	KMT2A (0.41)	AHRKMT2AMEN1ACKR3S1PR1
	SCHEMBL2430780	0.92	KMT2A (0.41)	AHRKMT2AMEN1ACKR3S1PR1
	SCHEMBL2429921	0.91	GRM4 (0.41)	JAK1
	SCHEMBL2429926	0.91	GRM4 (0.41)	JAK1
	SCHEMBL2431362	0.86	SMN1; SMN2 (0.41)	KMT2AJAK1
	SCHEMBL2431366	0.86	SMN1; SMN2 (0.41)	KMT2AJAK1
	SCHEMBL2432684	0.86	KMT2A (0.39)	AHRKMT2AMEN1ACKR3RAF1
	SCHEMBL2432854	0.86	KMT2A (0.39)	AHRKMT2AMEN1ACKR3RAF1
	SCHEMBL2429346	0.86	KMT2A (0.39)	AHRKMT2AMEN1ACKR3RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.