Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24284161 | 0.82 | PI4KA (0.37) | LMNACDC7DBF4 | |
| SCHEMBL25974700 | 0.79 | KDM4E (0.31) | KDM4EPKM | |
| SCHEMBL17755568 | 0.79 | KDM4E (0.33) | KDM4EPKMMEN1ALDH1A1LMNA | |
| SCHEMBL18876126 | 0.75 | KDM4E (0.31) | KDM4EPKMMEN1ALDH1A1LMNA | |
| SCHEMBL8737435 | 0.73 | KDM4E (0.34) | KDM4EPKMMEN1ALDH1A1LMNA | |
| SCHEMBL15339525 | 0.70 | PDPK1 (0.32) | PKM | |
| SCHEMBL9606750 | 0.69 | — | — | |
| SCHEMBL18876089 | 0.67 | — | — | |
| SCHEMBL8581391 | 0.65 | HTT (0.35) | ALDH1A1CDC7DBF4 | |
| SCHEMBL6127866 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022042331-A1 | HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-03-03 | — | — | WO | disclosed |