Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 8/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24043016 | 0.90 | SLCO1B1 (0.44) | SLCO1B1ABCB11PDE3BPDE3AHTR2A | |
| SCHEMBL22230632 | 0.88 | SLCO1B1 (0.49) | SLCO1B1ABCB11NPC1LMNANPSR1 | |
| SCHEMBL22230661 | 0.84 | SLCO1B1 (0.50) | SLCO1B1ABCB11PDE3BPDE3ACNR1 | |
| SCHEMBL22256932 | 0.81 | SLCO1B1 (0.43) | SLCO1B1ABCB11NPC1 | |
| SCHEMBL22230622 | 0.81 | SLCO1B1 (0.37) | SLCO1B1ABCB11NPC1EP300LMNA | |
| SCHEMBL29460168 | 0.81 | SLCO1B1 (0.59) | SLCO1B1ABCB11 | |
| SCHEMBL22256696 | 0.81 | SLCO1B1 (0.59) | SLCO1B1ABCB11 | |
| SCHEMBL22256960 | 0.80 | SLCO1B1 (0.43) | SLCO1B1ABCB11NPC1LMNANPSR1 | |
| SCHEMBL22230718 | 0.78 | SLCO1B1 (0.50) | SLCO1B1ABCB11NPC1LMNANPSR1 | |
| SCHEMBL22256698 | 0.78 | SLCO1B1 (0.48) | SLCO1B1ABCB11HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220079928-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST AND PREPARATION METHOD THEREFOR | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2022-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220079928-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST AND PREPARATION METHOD THEREFOR | LPAR1, LPAR2, LPAR4 | SLCO1B1 3685/4885ABCB11 3552/4885NPC1 520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.