Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.67 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.66 |
| ▸ | TNF | P01375 | 3/20 | 0.66 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.66 |
| ▸ | IL1B | P01584 | 2/20 | 0.66 |
| ▸ | BRD4 | O60885 | 1/20 | 0.66 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31034238 | 0.89 | CRBN (0.65) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL31034204 | 0.89 | CRBN (0.65) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL31727391 | 0.88 | CRBN (0.64) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL30511817 | 0.88 | CRBN (0.64) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL30511787 | 0.87 | CRBN (0.65) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL24132321 | 0.87 | CRBN (0.62) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL31727463 | 0.87 | CRBN (0.65) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL22511864 | 0.85 | CRBN (0.66) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL30938314 | 0.85 | CRBN (0.66) | CRBNIKZF3TNFIKZF1DDB1 | |
| SCHEMBL30069834 | 0.85 | CRBN (0.66) | CRBNIKZF3TNFIKZF1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |