SCHEMBL24293199

SCHEMBL24293199

CC1(C)c2ccccc2C2(c3ccccc3-c3ccccc32)c2cccc(-c3nc(-c4ccccc4)cc(-c4cccc(-c5ccccn5)c4)n3)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.41
TSHR P16473 3/20 0.39
HSD17B10 Q99714 2/20 0.39
MAPK1 P28482 1/20 0.39
GRM5 P41594 8/20 0.36
SMN1; SMN2 Q16637 7/20 0.36
RAB9A P51151 5/20 0.36
PKM P14618 4/20 0.36
NPC1 O15118 4/20 0.36
TP53 P04637 3/20 0.36
KDM4E B2RXH2 5/20 0.35
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 5/20 0.35
HPGD P15428 3/20 0.35
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MITF O75030 2/20 0.34
KLF5 Q13887 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21867776 0.92 PDK2 (0.40) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL24293240 0.91 TSHR (0.38) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL21868120 0.90 PDK2 (0.39) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL24293692 0.88 PDK2 (0.39) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL21868151 0.87 PDK2 (0.45) PDK2TSHRHSD17B10MAPK1SMN1; SMN2
SCHEMBL21868343 0.86 PDK2 (0.45) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL24293832 0.86 PDK2 (0.41) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL21868160 0.86 PDK2 (0.41) PDK2TSHRHSD17B10MAPK1SMN1; SMN2
SCHEMBL24293284 0.84 MAPT (0.39) PDK2TSHRHSD17B10MAPK1GRM5
SCHEMBL21868087 0.84 PDK2 (0.40) PDK2TSHRHSD17B10MAPK1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-20220123218-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG CHEM, LTD. (KR) 2022-04-21 US disclosed