Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429706 | 0.92 | SCD (0.58) | SCDKDM4ELMNASMN1; SMN2DCTPP1 | |
| SCHEMBL1095120 | 0.90 | SCD (0.59) | SCDKDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL1094940 | 0.89 | SCD (0.59) | SCDKDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL1094606 | 0.88 | SCD (0.67) | SCDKDM4ELMNASMN1; SMN2DCTPP1 | |
| SCHEMBL1096003 | 0.87 | SCD (0.67) | SCDKDM4ELMNASMN1; SMN2DCTPP1 | |
| Cyclohexane SCHEMBL2467082 | 0.86 | SCD (0.61) | SCDKDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL1095895 | 0.85 | SCD (0.65) | SCDKDM4ELMNASMN1; SMN2DCTPP1 | |
| SCHEMBL1096168 | 0.85 | SCD (0.62) | SCDKDM4ELMNASMN1; SMN2DCTPP1 | |
| SCHEMBL1096539 | 0.85 | SCD (0.66) | SCDKDM4ELMNASMN1; SMN2 | |
| SCHEMBL1095356 | 0.83 | SCD (0.65) | SCDDCTPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4782008-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| JP-2007500719-A | — | — | 2007-01-18 | — | — | JP | claimed |
| EP-1651606-A2 | PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2006-05-03 | — | — | EP | claimed |
| WO-2005011656-A2 | PYRIDYL DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2005-02-10 | — | — | WO | claimed |