Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374442 | 0.90 | PARP10 (0.45) | ACACBPARP10PARP15SLC6A2SLC6A4 | |
| SCHEMBL24302656 | 0.86 | SCN1A (0.46) | PARP10PARP15SLC6A2SLC6A4HTR3A | |
| SCHEMBL31632683 | 0.79 | PARP10 (0.43) | RORCCYP2D6ACACBBACE1BACE2 | |
| SCHEMBL20207072 | 0.79 | PARP10 (0.48) | BACE1BACE2PARP10PARP15FFAR4 | |
| SCHEMBL21736840 | 0.79 | PARP10 (0.48) | ACACBPARP10PARP15SLC6A2SLC6A4 | |
| SCHEMBL18374246 | 0.77 | ACACB (0.43) | ACACBPARP10PARP15FFAR4SCN9A | |
| SCHEMBL17658890 | 0.74 | NQO1 (0.48) | MEN1KMT2AFFAR4 | |
| SCHEMBL26343438 | 0.74 | ACACB (0.45) | ACACB | |
| SCHEMBL26343430 | 0.74 | ACACB (0.45) | ACACB | |
| SCHEMBL26343440 | 0.74 | ACACB (0.45) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022079432-A1 | 2-OXO-DIHYDROQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS GABA TYPE A RECEPTOR MODULATORS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-04-21 | — | — | WO | disclosed |