⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515639 | 1.00 | — | — | |
| SCHEMBL6668948 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31136160 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL20899155 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2430108 | 0.97 | — | — | |
| SCHEMBL23875760 | 0.78 | — | — | |
| SCHEMBL5540885 | 0.78 | — | — | |
| SCHEMBL14066052 | 0.78 | — | — | |
| SCHEMBL12868521 | 0.75 | DPP4 (0.32) | — | |
| SCHEMBL12868517 | 0.75 | DPP4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763990-B1 | PYRROLOPYRAZINE KINASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2017-02-22 | — | — | EP | claimed |
| US-8658646-B2 | Pyrrolopyrazine kinase inhibitors | HOFFMANN-LAROCHE INC. (US) | 2014-02-25 | — | — | US | claimed |
| CN-102574791-A | Enzymatic transamination of cyclopamine analogs | INFINITY PHARMACEUTICALS INC | 2012-07-11 | — | — | CN | claimed |
| US-20250074895-A1 | CDK2 INHIBITORS AND METHODS OF MAKING AND USING SAME | BLUEPRINT MEDICINES CORPORATION | 2025-03-06 | — | — | US | disclosed |
| CN-113330000-B | 3-Carbonylamino-5-cyclopentyl-1 FI-pyrrole compounds having inhibitory activity on CDK2 | 辉瑞公司 | 2024-12-24 | — | — | CN | disclosed |
| US-20240294506-A1 | CDK2 INHIBITORS | PFIZER INC. (US) | 2024-09-05 | — | — | US | disclosed |
| US-11773082-B2 | CDK2 inhibitors | PFIZER INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773082-B2 | CDK2 inhibitors | PFIZER INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11773082-B2 | CDK2 inhibitors | PFIZER INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-11718603-B2 | CDK2 inhibitors | PFIZER INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-11718603-B2 | CDK2 inhibitors | PFIZER INC. (US) | 2023-08-08 | — | — | US | disclosed |
| US-20070021494-A1 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION AND PHARMACOPEIA, INC. | 2007-01-25 | — | — | US | disclosed |
| US-20050119481-A1 | Novel amidine derivatives and the use of the same in pharmaceuticals | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | US | disclosed |
| CN-1173902-C | Racemization of optically active amines | �����ɷ� | 2004-11-03 | — | — | CN | disclosed |
| EP-1453794-A1 | NOVEL AMIDINE DERIVATIVES AND THE USE OF THE SAME IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2004-09-08 | — | — | EP | disclosed |
| CN-1154746-C | Improvement in enzymatic synthesis of chiral amines | — | 2004-06-23 | — | — | CN | disclosed |
| WO-2003053914-A1 | NOVEL AMIDINE DERIVATIVES AND THE USE OF THE SAME IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-07-03 | — | — | WO | disclosed |
| CN-1330618-A | Racemization of optically active amines | BASF AG (DE) | 2002-01-09 | — | — | CN | disclosed |
| CN-1308608-A | Substituted beta-amino acid inhibitors of methionine aminopeptidase-2 | ABBOTT LAB (US) | 2001-08-15 | — | — | CN | disclosed |
| CN-1292828-A | Improvement in enzymatic synthesis of chiral amines | CELGRO CO (US) | 2001-04-25 | — | — | CN | disclosed |