Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 12/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PDE6A | P16499 | 1/20 | 0.42 |
| ▸ | PDE6G | P18545 | 1/20 | 0.42 |
| ▸ | PDE6B | P35913 | 1/20 | 0.42 |
| ▸ | PDE6C | P51160 | 1/20 | 0.42 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24311983 | 0.89 | GAA (0.48) | GAAMAPTTHRBCSF1RKDM4E | |
| SCHEMBL24311984 | 0.87 | EGFR (0.52) | GAAMAPTTHRBCSF1RKDM4E | |
| SCHEMBL30629571 | 0.87 | MAPT (0.62) | GAAMAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL2724559 | 0.86 | CSF1R (0.58) | CSF1RNUDT1 | |
| SCHEMBL18987830 | 0.83 | MAPT (0.58) | GAAMAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL19957259 | 0.82 | GAA (0.51) | GAACSF1RKDM4EALDH1A1EGFR | |
| SCHEMBL30449564 | 0.80 | DPP4 (0.58) | GAAMAPTTHRBCSF1RKDM4E | |
| SCHEMBL2921747 | 0.80 | DPP4 (0.58) | GAAMAPTTHRBCSF1RKDM4E | |
| SCHEMBL7165177 | 0.79 | EGFR (0.58) | CSF1REGFRNUDT1 | |
| SCHEMBL31554519 | 0.79 | EGFR (0.58) | CSF1REGFRNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073470-A1 | INHIBITORS OF CGAS ACTIVITY AS THERAPEUTIC AGENTS | BELLBROOK LABS, LLC | 2022-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073470-A1 | INHIBITORS OF CGAS ACTIVITY AS THERAPEUTIC AGENTS | CGAS, STING1, IRF3 | GAA 78/4885MAPT 3533/4885THRB 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.