Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1017293 | 0.97 | EHMT2 (0.41) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22606155 | 0.94 | EHMT2 (0.42) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL22587506 | 0.78 | ACP1 (0.62) | KMT2AKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL22587451 | 0.77 | ACP1 (0.63) | KMT2AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22606446 | 0.76 | TLR7 (0.39) | KMT2AALDH1A1LMNAGAAADORA3 | |
| SCHEMBL29426252 | 0.76 | GAA (0.39) | ALDH1A1POLBGAAPDE10AADORA2A | |
| SCHEMBL22587446 | 0.76 | GAA (0.39) | ALDH1A1POLBGAAPDE10AADORA2A | |
| SCHEMBL3536147 | 0.75 | EGFR (0.58) | KDM4EALDH1A1LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL22587397 | 0.75 | GBA1 (0.63) | KMT2AKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL29426240 | 0.75 | GBA1 (0.63) | KMT2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3967691-A1 | PYRIMIDO FIVE-MEMBERED HETEROCYCLIC COMPOUND AND USE THEREOF AS MUTANT IDH2 INHIBITOR | Epitas Biosciences (Shanghai) Co., Ltd. (CN) | 2022-03-16 | — | — | EP | disclosed |